OpenAI is losing two of the architects of its most ambitious moonshots. Kevin Weil, who led the company’s science research initiative, and Bill Peebles, the researcher behind AI video tool Sora, both announced their departures on Friday. The exits come as OpenAI consolidates around enterprise AI and its forthcoming “superapp.”

The departures follow OpenAI’s decision to cut back on “side quests,” including customer-facing bets like Sora and OpenAI for Science. Sora, which was losing an estimated $1 million per day in compute costs, was shut down last month.

OpenAI for Science was the internal research group behind Prism, an AI-powered platform that promised to accelerate scientific discovery. It’s being absorbed into “other research teams,” according to Weil’s social media post announcing the news.

“It’s been a mind-expanding two years, from Chief Product Officer to joining the research team and starting OpenAI for Science,” Weil wrote. “Accelerating science will be one of the most stunningly positive outcomes of our push to AGI.”

The team had a short and bumpy road after its formal announcement in October 2025. Weil deleted a tweet claiming GPT-5 had solved 10 previously unsolved Erdős mathematical problems, but that claim fell apart immediately when the mathematician who runs the website erdosproblems.com called it out.

Weil’s departure comes a day after his team released GPT-Rosalind, a new model to accelerate life sciences research and drug discovery.