OpenAI and the U.S. Department of Energy (DOE) have signed a memorandum of understanding (MOU) to explore opportunities for further collaborations on AI and advanced computing in support of DOE initiatives, including the Genesis Mission. This work is part of OpenAI for Science⁠, our effort to help scientists accelerate discovery by pairing frontier AI models with the tools, workflows, and expertise of real research environments.

This MOU builds on OpenAI’s existing work with DOE’s national laboratories, where we’ve already deployed frontier models in real research environments and worked directly with scientists on high-impact problems.

The Genesis Mission⁠(opens in a new window) brings together government, national labs, and industry to apply advanced AI and computing to accelerate scientific discovery. The MOU establishes a framework for information sharing and coordination, and creates a path for the parties to discuss and develop potential follow-on agreements as specific projects take shape. Today, OpenAI also submitted detailed recommendations⁠(opens in a new window) to the White House Office of Science and Technology Policy on how the United States can strengthen science and technology leadership through AI. That filing outlines why we see 2026 as a “Year of Science” and why access to frontier AI models, compute, and real research environments is essential to accelerating discovery. The agreement with the Department of Energy reflects that vision moving into practice.

This announcement follows today’s Genesis Mission event at the White House, where Kevin Weil, Vice President of OpenAI for Science, joined DOE and other collaborators.