OpenAI’s collaboration with the U.S. National Labs builds on the long-standing tradition of the U.S. government collaborating with private industry to ensure that technological innovation leads to meaningful improvements in healthcare, energy, and other critical fields. It also reflects our ongoing commitment to empowering leading developers to safely leverage our models–transforming data into intelligence and intelligence into solutions, breakthroughs and discoveries.

The National Labs host approximately 15,000 scientists working across a wide range of disciplines to advance our understanding of nature and the universe. Under this agreement, OpenAI will work with Microsoft and will deploy o1 or another o-series model on Venado, an NVIDIA supercomputer at Los Alamos National Laboratory (LANL) where it will be a shared resource for researchers from Los Alamos, Lawrence Livermore, and Sandia National Labs. Venado was specifically designed to drive scientific breakthroughs in materials science, renewable energy, astrophysics, and more.

The Labs also lead a comprehensive program in nuclear security, focused on reducing the risk of nuclear war and securing nuclear materials and weapons worldwide. This use case is highly consequential, and we believe it is critical for OpenAI to support it as part of our commitment to national security. Our partnership will support this work, with careful and selective review of use cases and consultations on AI safety from OpenAI researchers with security clearances.

As advanced AI continues to reshape global geopolitics, this partnership provides a critical opportunity for OpenAI to help guide that transformation. This builds on our successful earlier collaboration⁠ with Los Alamos National Laboratory, where we worked closely with wet labs to assess the risks posed by the most advanced models in creating bioweapons (such as human-designed pandemics). We anticipate that this engagement will lead to broader safety collaborations across a variety of chemical, biological, radiological, and nuclear (CBRN) risks. Further, through our partnership with Microsoft as our preferred partner for AI compute infrastructure, and building on the valuable experience of this partnership with the Labs, we look forward to developing future projects together to support the U.S. government and the mission of ensuring AGI benefits all of humanity.